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Good relaxation is required in abdominal surgeries. Continuous infusion of nondepolarizing neuromuscular blocking agents with TOF monitoring helps to maintain constant serum levels and a stable paralysis state. We conducted an observational study in 50 ASA I and II patients, between 18–65 years undergoing elective abdominal surgeries after ethics committee approval. Aims And Objectives: Dose of Vecuronium required by continuous infusion. Spontaneous recovery time, quality of muscle relaxation . Material methods: Informed consent was taken. Induction done with Inj. thiopentone , Inj. Succinylcholine and vecuronium 100 g/kg. Vecuronium infusion @ 50 g/kg/hr was started at TOF–1 and maintained by titrating the infusion @ 5 g/kg/hr. Anesthesia was maintained with Nitrous oxide (70%) & Oxygen (30%). At closure of rectus sheath, infusion was stopped. Patient reversed with TOF–3 and confirmation of sustained head lift and hand grip and then extubated. Results: The infusion dose was 62.79  5.631 g/kg/hr, dose required in age group > 61 years (56.43  8.13 g/kg/hr) is less than < 40 years (63.77  5.86 g/kg/hr). The mean recovery time is 12.4  3.63 minutes. Conclusion: Continuous infusion technique of Vecuronium provides an adequate level of relaxation, hemodynamic stability and prompt recovery.

Vecuronium Requirement By Continuous Infusion Technique In Adult Patients During Fentanyl Nitrous Oxide – Oxygen Anesthesia.