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Objectives : The aim of study is to compare the preoperative and postoperative endothelial cell counts in Diabetic and Non-Diabetics in age matched population, after small incision cataract surgery. And to study the visual outcome in age matched diabetics and non diabetics after small incision cataract surgery. Study Design And Setting: This is a prospective, cohort, comparative study. It was carried out in the department of ophthalmology,J.L.N. Medical College and Hospital, AJMER. Two hundred (200) patients of senile cataract fulfilling the inclusion criteria were selected from the outpatient department of J.L.N. medical college, Ajmer. Patients in each group were operated by the same surgeon using similar surgical technique. These patients were divided into two groups. Group A (standard group) consisted of 100 patients who were nondiabetic and Group B consisted of 100 patients who were diabetic. After taking written consent, selected patients were admitted in the ward. A detailed history and ocular examination of all patients were done. Routine investigations including random blood glucose, HBA1C, urine complete and sensitivity test of xylocaine and sensorcaine of all the patients were done. Study Period: May 2013May 2014 Results: In our study pre-operative and post-operative mean ECD loss is accordingly showed gradual decline. In Diabetics Mean ECD Pre-operatively was 2610.37±262.65 , on Post-operative day 7 mean ECD was 2436.26±215.80,(p-0.0001).0n post-operative 6 weeks mean ECD was 2405.96±228.41,(p-0.0001) on postoperative 3 month mean ECD was 2363.35±270.46(p-0.0001) . In Non-diabetics Mean ECD Pre-operatively was2588.80±183.24,on Post-operative day 7 mean ECD was2500.50±200.00,(p-0.0001).On post-operative 6 weeks mean ECD was 2470.93±207.92 ,(p-0.0001). On post-operative 3 month mean ECD was 2435.27±221.39,(p-0.0001). The mean ECD decreases postoperatively. In Diabetics there was 6.66% loss in ECD on Post-operative day 7, 7.83% ECD loss on post-operative 6 weeks, 9.46%ECD loss on post-operative 3 months. In Non-diabetics there was 3.41% loss in ECD on Post-operative day 7, 4.55% ECD loss on post-operative 6 weeks, 5.66% ECD loss on post-operative 3 months.

iosr journal of dental and medical sciences

A Prospective Comparative Study of Central Corneal Endothelial Cell Count After Small Incision Cataract Surgery in Diabetic and Nondiabetic in Age Matched Population