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Electroconvulsive therapy has been widely used in the treatment of various psychiatric and somatic conditions such as obsessive compulsive disorder, postpartum psychosis, Parkinson's disease, depression, bipolar disorder and schizophrenia with varying degree of success. Currently, its utilisation has been constrained to limited conditionsdue to its neurocognitive side effects. Neurocognitive impairment associated with ECT treatment includes slow processing speed, verbal and memory deficits which manifest as post ictal confusion, anterograde and/or retrograde memory amnesia, or long-term subjective memory deficit in few patients. Memory deficits caused by ECT usually last for less than six monthsafter the end of ECT treatment, but there is no impairment of acquisition and retention of new memories.Propofol and liothyronine prevent memory deficits post-ECT treatment through different mechanisms.

Neurocognitive Effects of Electroconvulsive Therapy in Psychiatric Disorders, Mechanism of Action And its Prevention: Review Article