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Background and objectives: Recent studies have elucidated thealterations in hemostatic profile in chronic renal disease. This study aims at evaluating the changes in the hemostatic profile in stage III and IV patients of chronic renal disease. Material and methods: This case-control study included chronic renal failure patients of stagesIII , IV and an equal number of matched healthy volunteers. Serum Urea, Creatinine, plasma fibrinogen, bleeding time, prothrombin time, APTT, platelet count, D-Dimer and nitric oxide were estimated in all the patients. Results: a significantly increase plasma fibrinogen level

Plasma Fibrinogen Level, Homeostatic Alterations And Nitric Oxide Levels in Chronic Renal Disease