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Background: Smoking has acute deleterious effects on the blood pressure and sympathetic tone, and it reduces the myocardial oxygen supply. HRV is recognized as an effective and noninvasive tool for evaluating autonomic nervous system regulations of the heart. AIM: The aim of our study was to observe the effect of cigarette smoking on heart rate variability in healthy adult smokers in the age group of 20 -60 years. Material And Method: A cross-sectional (observational) study was conducted on 60 healthy adult smokers and 60 healthy nonsmokers in the age group of 20-60 years. Heart Rate Variability (HRV) was recorded by Physio Pac (PC-2004). The data consisted of anthropometric parameters analysis, Time Domain Analysis and Frequency Domain Analysis in smokers and controls. Data collected was analysed statistically. Results: The difference in mean RR, mean Heart Rate, RMSSD (the root mean, square differences of successive NN intervals), NN50 (the number of Interval Differences of successive NN intervals greater than 50 ms), pNN50 (a measure of the number of adjacent NN intervals which differ by more than 50 ms), LF/HF ratio was found to be statistically highly significant. The difference in mean STD (SDNN)( The standard deviation of intervals between normal beats), LF(low frequency) power, HF(high frequency) power, HF power% was found to be statistically significant. Conclusion: This suggests increased sympathetic activity and decrease in parasympathetic activity. Smoking severely affects the cardiac autonomic functions which is evident with the study of Heart Rate Variability, so the HRV should be included in routine investigations to assess the severity of cardiac involvement in chronic smoke.

Effect of Cigarette Smoking on Heart Rate Variability in Health Adult Smokers in The Age of 20-60 Years