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Background: With recent advances in the field of caries research and diagnosis it is possible to remineralize early carious lesions or white spot. The present in vitro study was carried out to evaluate and compare the remineralization of artificially created subsurface enamel lesion, using three different remineralizing agents. Method: 60 enamel specimens were divided into 3 groups, with 10 control and 10 study specimens. After immersion in demineralizing solution for 48 hours the enamel specimens were treated with following remineralizing agents, Group Amousse containing Casein phosphopeptide amorphous calcium phosphate (CPP-ACP), Group Bdentifrice containing functionalized tricalcium phosphate (fTCP) with 0.21% sodium fluoride, and Group Ca dentifrice containing Novamin. After 15 days of treatment, all the specimens were indented to evaluate Vickers microhardness of enamel specimens using Reicherts microhardness testing machine. The data was analysed using paired t-test and ANOVA. Results:In all the three groups, there was statistically significant difference in microhardness values of enamel specimens before and after treatment with the agents (p < 0.05). Mean increase in microhardness value was more in Group 2 (f-TCP with 0.21% sodium fluoride). No significant difference was observed between the mean increase in microhardness across CPP-ACP, fTCP +0.21% sodium fluoride and novamin groups (p > 0.05). Conclusion: The microhardness of enamel specimens significantly increased after treatment with remineralizing agents for 15 days. Thus, all the three agents are effective in remineralizing the enamel subsurface lesion.

Comparative Analysis of Remineralizing Potential of Three Commercially Available Agents- An in Vitro Study