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Isoflurane is commonly used agent in neuro anaesthesia. But desflurane has lowest blood gas partition co efficient and has rapid recovery profile. Hence it may have useful role in spine surgeries. There is paucity of data regarding comparison of desflurane, sevoflurane and isoflurane in neuroanaesthesia in adult patients in a single study. Hence the need of present study. Ninety ASA I/II patients aged 20-60 yrs were randomly allocated into three groups of thirty each. Group D, Group S, group I received desflurane, sevoflurane and isoflurane respectively. The primary outcome studied was time to emergence: the time from discontinuation of anaesthetic agents to open eyes either spontaneously or in response to verbal commands. The secondary outcomes studied were time to extubation, time to recovery, haemodyanamic variations and complications if any. Data were analyzed using chi square, student t and ANOVA tests as applicable. p value<0.05 was considered statistically significant.The mean emergence time was shorter in desflurane group (3.32±2.28 min) as compared sevoflurane( 6.13±2.56 min) and isoflurane(7.93±2.02 min) groups (p<0.001) .Similar statistical difference was achieved in extubation and recovery times.Hence desflurane is better suited volatile halogenated agent for adult patients undergoing spine surgeries performed under general anaesthesia.

iosr journal of dental and medical sciences

A Comparison of Emergence Characteristics with the use of Isoflurane, Sevoflurane and Desflurane in Patients Undergoing Spinal Surgeries under General Anaesthesia