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Nonsteroidal ant-inflamatory drugs are commonly prescribed in out-paient orthopaedic department for acute inflammatory conditions like soft tissue injuries,sports injuries,trauma ;post surgery conditions or chronic inflammatory conditions like lumbago,rheumatoid arthritis and osteoarthritis.To avoid side effects of these NSAIDS ,common gastroprotecive drugs prescribed are proton pump inhibitors,H2 blockers, sucralfate, antacids and misoprostol. Study Design: A cross-sectional,single centre drug utilization was conducted.Prescriptions were obtained from patients attending OPD.The prescription pattern of NSAIDS,gastroprotective drugs or co-administration were evaluated. Results: A total of 1500 prescriptions were evaluated;in which 1439(95.9 percent) prescriptions contained nonsteroidal anti-inflammatory drugs with gastroprotective drugs.The most common gastroprotective agents combined with nonsteroidal antinflammatory drugs were PPI(proton pump inhibitors)[52.46percent] followed by H2 receptor antagonists[32.73],while antacids[14.73] were prescribed least.

iosr journal of dental and medical sciences

Co-Administration of Nonsteroidal Ant-Inflammtory Drugs and Gastropotective Drugs in Orthopaedic Out Patient Department of a University Hospital in Kashmir