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Background & objectives: Human immune deficiency virus (HIV) is a neurotropic virus which causes variety of neurologic manifestations either due to opportunistic infections and neoplasm or direct effects of HIV on nervous tissue. The objective of present study was to find out various neurological manifestations in HIV patients and their relation with CD4 counts. Methods: The present study included 200 symptomatic HIV patients attending ART center at tertiary care center of north India in the time period December 2012 to October 2014 were study. Out of which 57 patients were presented with neurological complications, all study subjects were thoroughly interviewed with detailed clinical history along with general physical examination, systemic examination and detailed neurological examination. Results: Neurological complications were seen in 57 patients out of 200 and the commonest manifestation was tubercular meningitis in 47.37% patients followed by cryptococcal meningitis in 14%, HIV associated dementia in 8.80%, bacterial meningitis in 7%, progressive multifocal leucoencephalopathy in 5.30%, peripheral neuropathy in 5.30%, toxoplasmosis in 3.50%, cerebrovascular accident in 3.50%, cranial tuberculoma in 3.50% and acute inflammatory demyelinating polyneuropathy in 1.80% of HIV patients. 74.19% patients had CD4 count <200/mm 3 and 22.81% had CD4 count between 200-500/mm 3 . Conclusion: The prevelance of neurological manifestation in HIV patients was 28.50% and opportunistic infections were the leading cause of neurological disorder. Central nervous system infections, intracranial mass lesion, stroke and HIV associated dementia were more common in patients with a CD4 count less than 200/mm 3 .

Clinical Profile of Neurological Manifestations Among HIV Positive Patients And Their Correlation with CD4 Count