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Objective: To explore the clinical efficacy of the use of polymethylmethacrylate (PMMA) augmentation of a cannulated and fenestrated pedicle screwfixation for the treatment of lumbar degenerative disease accompanied withosteoporosis. Methods: Thirty-one patients of lumbar degenerative disease accompanied with osteoporosisfrom Jun 2008 to Jan 2013 were selected .They were 11 males and 20 females withaverage age of 73. 5 years including lumbar degenerative stenosis 14 caseslumbar intervertebral discherniation combined with segmental instability 9 caseslumbar degenerative spondylolisthesis 6 casesandlumbar degenerative scoliosis 2 cases. The patients were treated with lumbar canal decompression, fusion and polymethylmethacrylate (PMMA) augmentation of a cannulated and fenestrated pedicle screw fixationaccording to their clinicalfeature and imaging. Results: All cases were followed up for 40 months (range,36-48months). No screw breakage, rod breakage, screw extraction, loosening, pseudoarticulation formation, or incision infection wasfound.The postoperative VAS score wasremarkably lower than preoperative score (P < 0.05). The JOAscore were improved significantly (P < 0.05). Conclusion: For patients suffering from lumbar degenerative disease accompanied with osteoporosisPMMA augmentation of a cannulated and fenestrated pedicle screwfixation was helpful for increasing the stabilization of screw and preventing from loosen and dislocation of the screwstherefore beneficial for improvement and maintenance of clinical efficacy. Key word: Osteoporosis; cannulated and fenestrated pedicle screw; PMMA; Lumbar degenerative disease

iosr journal of dental and medical sciences

Polymethylmethacrylate (PMMA) Augmentation Of A Cannulated And Fenestrated Pedicle Screw Fixation For Stabilization Of The Lumbar Degenerative Disease Accompanied With Osteoporosis