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Infection with Methicilln resistant Staphylococcus aureus (MRSA) was not very uncommon in the Neonatal Intensive Care Units(NICU) at present. In this study we report an outbreak of MRSA infection and its successful control in a tertiary care teaching hospital, Kolkata between September 2009 and June 2010. Twelve MRSA strains were isolated and identified conventionally following Clinical and Laboratory Standards Institute (CLSI) guidelines, from various clinical specimens, sent from the NICU. Subsequently, an infection control team was formed and infection control measures including isolation of infected babies, maintenance of hand hygiene , screening for colonization with MRSA, treatment of infected as well as carrier were implemented in NICU. Demographic data were collected from clinical records. Four (4) care givers were found to be colonized with MRSA strains. Antibiogram pattern of 6 infected babies matched with the MRSA strains isolated from the colonized attendant and nursing staff. Prematurity, low birth weight and gavage feeding were established risk factors for infection with MRSA in this study. Nine neonates were found to be colonized with MRSA though none was infected with the same strain. Following control measures, only one case of MRSA was detected in October 2009 thereafter no case of MRSA was reported till June 2010.MRSA outbreak acted as an alarm to the infection control committee of this tertiary care centre of eastern India for continuous monitoring and screening for MRSA in NICU.

Outbreak of Methicillin Resistant Staphylococcus aureus in Neonatal Intensive Care Unit in a Tertiary Care Hospital in Kolkata