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Cerebrospinal fluid (CSF) rhinorrhea is the result of an osseous defect at the skull base coupled with a disruption of the dura mater and arachnoid with a resultant pressure gradient leading to the CSF leak. Cerebrospinal fluid (CSF) rhinorrhea is a potentially dangerous condition as the risk of intracranial infection is increased if it persists. Therefore, accurate preoperative localization of the site of leakage as well as its appropriate management is mandatory. We here report two children with CSF rhinorrhea due to congenital anterior skull base defect, complicated by recurrent pyogenic meningitis, underwent surgical repair with uneventful post-operative period. In this article, etiologies, laboratory investigation including imaging and management are also discussed in brief.

CSF rhinorrhea complicated by recurrent pyogenic meningitis due to congenital anterior skull base defect: Report of two cases