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Objective: Dengue infection is a major public health concern in tropical and subtropical World and an important differential diagnosis of fever during pregnancy influencing the obstetric outcome. In this context, we present our experience with clinical spectrum and course of Dengue fever in our series of obstetric cases. Methods: A retrospective analysis of pregnant women diagnosed with dengue fever during pregnancy between August to October 2012 (15 months) was performed with regards to its clinical course, co-morbidities, obstetric outcome and maternal complications. Results: The cohort included 19 cases of Dengue fever complicating pregnancy with one case of hemorrhagic fever. The age of cohort was 24.3± 3.5 (18-33). Fever was the commonest clinical manifestation. There was no major bleeding diathesis. Preterm delivery and intrauterine death occurred in 3 cases each. All the complications and fetal deaths were related to hyperpyrexia. There was no maternal mortality. All the cases received only supportive therapy, antipyretics and ensuring adequate hydration. There was one neonatal death due to meconium aspiration syndrome. Conclusions: 1) Early diagnosis of DF relies on high index of suspicion and supportive therapy with an aim to maintain normothermia is the cornerstone of therapy (Key Words: Dengue fever; Pregnancy; HELLP Syndrome)

Clinical spectrum and course of Dengue Fever during Pregnancy: Institutional experience from South India