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Enterococci have traditionally been regarded as low grade pathogen , have emerged as an increasingly important cause of nosocomial infections in the last decade.Despite increasing reports of VRE in different countries ,there is scanty data on this issue from india especially in the Eastern zone. A total of 157 enterococci were isolated from various clinical specimens (urine,pus& wound swabs,blood and throat swabs body fluids), received in the Microbiology laboratory of a tertiary care hospital in eastern India during the period between July2010 to June2011. Out of 157 enterococcal isolates52 showed vancomycin resistance by Kirby Bauer disc diffusion method. Of the 52 isolates 11 showed vancomycin resistance with an MIC >6μg/ml and 2 showed teicoplanin resistance with an MIC >8μg/ml done by agar dilution method following CLSI guidelines. Thelevel of resistance were further evaluated by determining MIC using “E" Test strip of vancomycin and teicoplanin. Out of 11 VancomycinResistance Enterococci (VRE),9 were characterized as VanB and 2 were found to be VanA phenotype.Out of 10 uncommon enterococcal isolates(07E.casseliflavus& 03 E.gallinarum) 09 showed increased MIC to vancomycin (02 04μg/ml).41.4% isolates showed high level aminoglycoside resistance.

EnterococcalInfections And Its Antimicrobial Resistance With Special Reference To VRE And HLAR In A Tertiary Care Hospital In Eastern India