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We compared secondary and primary infertile women of reproductive age in terms of the levels of FSH and LH. This investigation was carried out at the Jos University Teaching Hospital (JUTH), Nigeria. 150 women within the reproductive age of 25-34 years, categorized into control (n=50), secondary infertile (n=50) and primary infertile (n=50) were randomly drawn for the study. A fasting morning blood sample was obtained from the patients during the follicular phase of the cycle for serum FSH and LH investigation by enzyme-linked immunosorbent assay (ELISA) methods. SerumFSH results for secondary infertile groupexpressed as mean±SD is 6.07±2.53 [t-test value of 0.12 (p<0.05) when compared with the control], primary infertile group is 10.87±11.39, [t-test value of 0.02 (p<0.05) when compared with the control]. Serum LH results for secondary infertile group expressed as mean±SD value is 4.92±3.54 [t-test value of 0.02 (p<0.05) when compared with control], primary infertile is 8.61±5.76 [(t-test value of 0.01 (p<0.05) when compared with control].In the secondary infertile group, 2% had FSH serum levels below, 92% within and 6% above the normal range limits. For LH, 2% have serum levels below, 90% within and 8% above normal range limits. In the primary infertile group, 18% have FSH levels below, 46% within, and 36% above the normal range limits. For LH, 4% have levels below, 56% within, 40% above the normal range limits.Proportionality investigation between FSH and LH levels shows a direct proportionality. There is no significant difference between secondary infertile group and the control group, but there is a significant difference between the primary infertile group and the control in terms of FSH and LH levels. Proportionality investigation suggests a direct proportionality between FSH and LH.

iosr journal of dental and medical sciences

A Comparative Study of the Serum Levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH) During Follicular Phase in Secondary and Primary Infertile Women of Reproductive Age