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Spinal anaesthesia is one of the most common procedure used in clinical anaesthesia practice. It has the advantage that profound nerve block can be produced in a large part of the body by the relatively simple injection of a small amount of local anaesthetic.Hypotension is one of the most common event encountered with the procedure Hypotension and bradycardia during spinal anesthesia are common and may relate to severe adverse events such as cardiac arrest or death. Preventive measures include fluid preload, lateral tilt, and use of vasopressors. Search is still on for the pharmacological agents that can provide hemodynamic stability with neuraxial blockade. I. Objective The prolongation of spinal anesthesia by using opioids and α2 agonist like Clonidine through the oral,intravenous and spinal route has been known. The new α2 agonist, dexmedetomidine has also been proved to prolong the spinal anesthesia through the intrathecal route.The aim of the study is to compare dexmedetomidine as an adjunct to bupivacaine in comparison to bupivacine alone & its effect on various haemodynamic factors. Methods Fourty six patients of ASA grade I and II between 18-58yrs of age of either sex, admitted in RIMS,RANCHI (Jharkhand), scheduled for elective lower abdominal & lower limb surgical procedure were included The study protocol was approved by Institutional Ethical Committee and written informed consent was obtained from all patients. The pre-anaesthetic check-up included a detailed medical and surgical history, and any previous anaesthetic exposure with its outcome. General examination includes general condition, built, weight, pulse rate, blood pressure, respiratory rate, and presence of cyanosis, anaemia, clubbing, jaundice or edema. A careful thorough systemic examination was done to rule out any cardiovascular, respiratory, gastrointestinal and neurological or any other systemic illness.Routine biochemistry investigation included haemoglobin, total leucocyte count, differential leucocyte count, blood sugar, blood urea, and serum creatinine, were done in all patients. ECG and X-Ray Chest were done in patients where indicated and in those over 40 years of age along with other relevant investigation. After taking detailed history and thorough clinical examination, the patients were excluded from the study on the basis of below mentioned criteria: Patients with systemic hypertension, hepatic dysfunction, renal dysfunction, endocrine dysfunction, cardiac dysfunction, morbid obesity (body weight more than 20% of the ideal body weight),Other exclusion criteria were patients with known drug hypersensitivity, those on antihypertensive medication or antidepressant drugs and those who refused to give consent.  Inclusions

A Comparative Study Between Dexmedetomidine As An Adjunct To Bupivacine In Comparison To Bupivacine Alone In Haemodynamic Stability