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Objective: To estimate the level of umbilical cord TSH in term Neonates in Manipur Study design and setting: Cross-sectional study conducted in the Dept. of Biochemistry in collaboration with Dept. of Pediatrics and Dept. of Obstetrics &Gynaecology, Regional Institute of Medical Sciences (RIMS), Imphal (Manipur). Materials and Methods: Blood samples were collected from the umbilical cord of 500 term newborn infants at the time of birth of the baby. Thus a mixed cord blood sample including both from the umbilical artery and vein was obtained and Thyroid stimulating hormone level (TSH) was estimated within 24 hrs by enzyme immunoassay. Results: The birth weights ranged between 2.5 to 4.0 kg. The male: female ratio was 205:295. TSH values ranged from 2.8-52.3mlU/L. The mean value was 13.264mlU/L. A cut –off value of 20 mlU/L was used for recall testing of complete thyroid profile (T3, T4 and TSH). Forty seven infants were recalled for repeating complete thyroid profile

Assessment of umbilical cord TSH in term Neonates in Manipur