English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

The ethanol extract of Bryophyllum pinnatum was investigated for possible anti-nociceptive and anti-inflammatory effects in mice and rats was carried out using acetic acid-induced abdominal contractions in mice and formalin-induced hind paw edema in rats. . Three doses of the extract (50, 100, and 200mg/kg body weight) were used intraperitoneally for both anti-nociceptive and anti- inflammatory studies. There was a significant effect (P<0.05) for the anti-nociceptive study, the highest activity resides at the lowest dose 50mg/kg body weight of the extract, while for the anti-inflammatory study (P<0.05) the activity resides more at the dose of 100mg/kg. Preliminary phytochemical screening of the extract revealed the presences of alkaloid, triterpenoid, saponin, glycerin, flavonoid,, glycerin and steroid. The intraperitoneal LD50 is 774 mg/kg body weight in mice. The results support the local use of the plant in painful and inflammatory condition..

Antinociceptive and Anti-Inflammatory Activities of Ethanol Extract of Bryophyllum Pinnatum Laboratory Animals