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The present study has been undertaken to evaluate the efficacy of umbilical vein oxytocin in minimising the blood loss during third and fourth stage of labor in comparison with umbilical vein injection of saline only and with systemic methylergometrine. We performed a randomised control study involving three hundred women who were randomized into 3 groups of hundred women in each group.. Group 1 received umbilical vein injection of oxytocin. Group 2 received intraumbilical vein saline injection while subjects in group 3 were managed with systemic methylergometrine,0.2mg intravenous at the delivery of anterior shoulder The primary outcome was measured in terms of duration of third stage of labor,blood loss, number of undelivered placenta and need for further oxytocics. Secondary outcomes were in terms of pre-delivery and post-delivery haemoglobin and haematocrit estimation.Intraumbilical oxytocin significantly shortens the duration of third stage of laborwhen compared with intraumbilical saline as well as systemic methylergometrine. It is also effective in reducing the amount of blood loss when compared to intraumbilical saline injection, but it was comparable in efficacy to methylergometrine in preventing amount of blood loss.

A Randomized Controlled Study of Prophylactic Use of Umbilical Vein Oxytocin in The Management of Third Stage of Labor.