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Objective: To describe the epidemiological profile of Diabetes Mellitus in Piauí State, in the Northeasternregion of Brazil, between 2002 and 2012. Methods: An epidemiological study, with retrospective collection.Secondary data were used from HiperDia, system available in the DATASUS. Results: There were recorded8551 cases, of which 75.4% of type 2 and 24.6% of type 1. In all the years of the study, the largest number ofcases occurred in the age group of 40 to 59 years old, both the type 1 and type 2. The female gender was the mostaffected by the disease (60.37%). From the associated comorbidities, the one that presented a higher frequencywas kidney disease both in patients with DM type 1 (3.4%), as in patients with type 2 DM (2.2%). Conclusion:The knowledge of the epidemiological profile is essential for the development of more effective health actionsgeared to the reality of DM in Piauí State, in the Northeast of Brazil

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Perfil epidemiológico do diabetes mellitus em um estado do nordeste brasileiro Epidemiological profile of Diabetes Mellitus in a northeastern brazilian state