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Objective: to validate the content of the operational definitions of the construct "non-acceptance to hypertension treatment". Method: a methodological study of content validation. It was performed an integrative review that showed four dimensions of nonacceptance: person, disease/treatment, health care and environment. Thirty-six operational definitions were developed in the context of these dimensions. The settings were evaluated by a panel of 17 experts. The Content Validity Index (CVI) was calculated for each operational definition, and the binomial test was performed. Results: among the 36 developed operational definitions, 20 were validated with excellent IVC (≥0,81) with p<0,005; 11 suffered adjustments and were re-evaluated, five were excluded. Conclusion: the design and validation of these operational definitions as a specific event of nursing contribute to the consolidation of attributes of concepts that ultimately foresee the demarcation of nursing science

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Validação de conteúdo das definições operacionais da não adesão ao tratamento da hipertensão arterial Content validation of the operational definitions of non-acceptance to hypertension treatment