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USCPACK Software from University of Carolina is one of the pioneers of computerized drug dosage system. This software uses Bayesian method. The algorithm that used in this software is known as NPEM (Non Parametric Expectation Maximization). After knowing how USCPACK work, then we made new software that has the same use like USCPACK but with new algorithm that different from NPEM. These paper will describe the how to make the software based on NPAG algorithm.   Abstract in Bahasa Indonesia:  Software USCPACK buatan University of Carolina merupakan salah satu pelopor dimungkinkannya penentuan dosis obat persatuan waktu tertentu untuk pasien secara umum menggunakan komputer. Software ini bekerja dengan menggunakan metode dasar Bayesian. Algoritma yang digunakan oleh software ini adalah NPEM (Non Parametric Expectation Maximization). Setelah mengetahui cara kerja dari USCPACK maka dibuatlah sebuah software pendosisan obat menggunakan algoritma non parametrik lain selain NPEM. Paper ini akan membahas pembuatan software pendosisan obat menggunakan algoritma newton – raphson dalam penentuan dosis obat terkomputerisasi.  Kata kunci: Pendosisan terkomputerisasi, optimasi, Bayesian, NPEM, Newton Raphson, USCPACK

PENGGUNAAN ALGORITMA NEWTON – RAPHSON UNTUK MEMBUAT SOFTWARE PENENTUAN DOSIS OBAT