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The therapeutic properties of Goya extra virgin olive oil in albino rats orogastrically dosed with Salmonella Typhi were accessed in this study. Both the invivo and invitro assays were used in assessing the antimicrobial activity of Goya extra virgin olive oil. Thirteen microorganisms including eight bacteria and five fungi were used in the invitro bioassay. Comparison of the antimicrobial efficacy of olive oil and commercial antibiotics revealed ofloxacin, gentamicin as well as the olive oil to be potent against the test organisms. The invivo bioassay were carried out using twenty albino rats randomly assigned into four study groups of five rats per group. The groups orogastricallly dosed with Salmonella typhi revealed that the animals showed depressed activity and weakness such as slow movement, anorexia, falling fur and rough hair coat, light soft faeces, ocular discharge and loss of weight. Following separate treatments of the rats with antibiotic (Ofloxacin) as well as Olive oil, all the characteristic symptoms of the disease decreased with time. The treated animals gained more appetite for food and water as evidenced by an increase in their Original Research Article

Therapeutic Effect of Goya Extra Virgin Olive Oil in Albino Rat Orogastricallly Dosed with Salmonella typhi