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Background: Labor duration is one of the factors affecting the pregnancy outcome. Objective of the present study is to determine the effect of honey saffron syrup on the labor progression in nulliparous women. Methods: The nulliparous women with inclusion criteria were randomly divided into three equal groups. For first group, the saffron syrup prepared with honey and for second group, saffron syrup prepared with sugar and in the control group the placebo were orally administered every two hours. Collected data were analyzed using Fisher’s test, ANOVA with Fisher’s post hos test and Repeated measure statistical method with p <0.05 as significant. Results: The mean of labor duration in the two intervention groups was significantly shorter than the control group (p=0.000). The duration of the first stage of labor in the honey saffron syrup group was significantly shorter than the sugar saffron syrup group (p=0.016). Conclusion: Administration of saffron syrup with honey shortened the time of first, second and third stage of labor. Original Research Article Ghaderi et al.; JPRI, 28(4): 1-8, 2019; Article no.JPRI.47980 2

The Effect of Honey Saffron Syrup on Labor Progression in Nulliparous Women