English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Aim: Mangifera indica is a plant with several phytoconstituents which accounts for its tradopharmacological uses such as treatment of syphilis, anemia, diabetes, diarrhea, mouth wound, ulcer, leucorrhea, fever, liver diseases, urinary tract infection, asthma, rheumatism, cough, colon cancer and dysentery. The present study was aimed at identifying and characterizing some of the active principles from root of the plant. Places and Duration of Study: The isolation and characterization of the compounds was carried out at the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), University of Strathclyde, Glasgow, United Kingdom between October, 2018 to February, 2019 while the bioassay analysis was done at Ahmadu Bello University, Zaria, Nigeria. Methodology: The root powder was subjected to Soxhlet extraction with ethyl acetate to obtain the crude extract, which was fractionated on column using hexane, and ethyl acetate in increasing ratios. The isolated components were tested for their antimicrobial activities against some plants and animal pathogens at Ahmadu Bello University, Zaria, Nigeria. Original Research Article Nna et al.; JOCAMR, 7(4): 1-10, 2019; Article no.JOCAMR.50048 2 Results: White crystals were obtained which on spectra analysis (IR, 1H-NMR, 13C-NMR, 2DNMR) were identified as mixture of stigmasterol and β-sitosterol. The isolated compounds exhibited appreciable antimicrobial activities against some microbes, thus confirming the many ethnomedical uses of the plant. Conclusion: The compounds isolated were identified as stigmasterol and β-sitosterol. The pathogens showed moderate sensitivity towards the isolated compounds in the study.

Stigmasterol and β-sitosterol from the Root of Mangifera indica and Their Biological Activities against Some Pathogens