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Acute Salmonella typhi prosthetic joint infection (PJI) is a rare event. In Endemic areas one needs to be cautious if the patient is immunocompromised. We report a case of bilateral simultaneous PJI of the knee in a 60-year-old lady who was not immunocompromised. The patient presented on Post op Day 5 with Fever and local signs suggestive of infection. As this was an Early PJI she was successfully treated with Debridement, Poly exchange and Intravenous and oral antibiotics for 6 weeks. This case highlights the fact that in patients living in these areas and in seasons where incidence of enteric fever is high, patients should be screened preoperatively for Salmonella infection by history and stool cultures. To our knowledge this is the first case report of Early Bilateral Simultaneous infection with Salmonella typhi. Case Report Raviraj et al.; JAMMR, 29(4): 1-8, 2019; Article no.JAMMR.48043 2

Early Infection of Bilateral Total Knee Arthroplasty with Salmonella typhi: Case Report and Review of Literature