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· This article explores the Skillman Foundation's shift in its approach to fulfilling its mission to improve the lives of children and youth and to making grants – moving from a traditional grantmaker to a place-based investor and change-maker. · Three aspects of Skillman's approach have directly shaped the evolution of its youth-development investments: recognizing Detroit's economic, social, political, and environmental challenges; articulating overarching goals to provide direction and setting priorities for the scope and focus of its program-matic work; and using rapid learning to inform strategic decisions and social-innovation practices designed to tackle deeply entrenched problems. · This article reflects on the foundation's evolution over two decades of learning, prioritization, and strategic action in its efforts to build and sustain outcome-focused youth-development systems. Introduction Since 1960, the Skillman Foundation has been dedicated to improving the lives of children and youth in metropolitan Detroit. The city, which has the highest child poverty rate in the country,

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From Citywide to Neighborhood-Based: Two Decades of Learning, Prioritization, and Strategic Action to Build the Skillman Foundation’s Youth-Development Systems