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Apama siliquosa Lam is a folklore drug which is used to treat diarrhoea. It is locally known as Chakranike. The root of the drug is said to be effective in treating diarrhoea, cholera. The complete description of the drug is not available in the texts of Ayurveda. In this study an attempt is made scientifically to identify the drug Apama siliquosa.Lam. Pharmacognostical and phytochemical study of the drug is done to standardize the plant. The macroscopic as well as microscopic features of the plant is observed. Physico-chemical parameters such as loss on drying, total ash, acid insoluble ash, alcohol soluble extract, water soluble extract was assessed. Preliminary phytochemical screening was conducted by chloroform, benzene, methanol and petroleum ether extracts of the drug A. siliquosa. Lam. It revealed the presence of alkaloids, carbohydrates and glycosides. TLC, HPTLC plates of the drug were also developed and Rf value, color of the spot, densitometry scan was recorded.

PHARMACOGNOSTICAL AND PHYTOCHEMICAL STUDY OF CHAKRANIKE (Apama siliquosa Lam): A FOLKLORE DRUG