English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

T his study aimed to evaluate antibacterial and antifungal activities and exhaustive extraction yields of the aqueous and organic extract s of V erbascum sinuatum L . , against possible human pathogens, which are the fungus Candida albicans , gram positive bacteria Bacillus subtilis, Staphylococcus aureus , Staphylococcus epidermidis and the gram negative bacteria Eschrichia coli and Pseudomonas aeruginosa . Well diffusion method was used in screening of antimicrobial activity for the plant extracts, in which the diameters of inhibition zones were measured and compared to a positive control. S erial dilution method wa s used for measuring the minimum inhibition concentrations for each microorganism. In well diffusion method, the plant’s aqueous extract has antimicrobial activity to all the tested organisms except Pseudomonas aeruginosa and C andida albicans, with variabl e diameters of inhibition zone. The percent inhibition c o mpared to the positive control imipene m was 39.13 % for Staphylococcus aureus , 37.5 % for Staphylococcus epidermidis, 30.55 % for Eschrichia coli and the least 30.43 % for Bacillus subtilis . The orga nic extract exhibited inhibition activity 26.08 % against Bacillus subtilis and 50 % against Eschrichia coli . In the serial dilution method, the aqueous extract exhibited inhibition for all the test microorganisms. At initial concentration of 20 mg/ml, the lowest MIC value was for Staphylococcus aureus 1.28 µg/ml, and highest for S taphylococcus epidermidis 4000 µg/ml. The MIC values for P seudomonas aeruginosa 160 µg/ml, 800 µg/ml for B acillus subtilis , 800 µg/ml for Eschrichia coli and 32 µg/ml for C andida albicans respectively . This study showed that V . sinuatum extract has a broad spectrum activity against gram positive and gram negative bacteria, as well as anti candidal activity.

SCREENING ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES AND EVALUATION OF THE EXHAUSTIVE EXTRACTIONS YIELDS FOR VERBASCUM SINUATUM L.