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Antibodies to extractable nuclear antigens (ENA) were determined in autoimmune graft-vs-host F1 (GVH F1) mice by the immunoblotting method. Major populations of anti-ENA known in human sera including anti-Sm were not detected. It is thus conceived that different kinds of ENA proteins may be recognized by human autoimmune and GVH F1 sera.

ANTIBODIES TO EXTRACTABLE NUCLEAR ANTIGENS IN GRAFT-VS-HOST F1 MICE AS DETERMINED BY IMMUNOBLOTTING: ABSENCE OF ANTI-SM ANTIBODY