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Adenovirus type 8 (Ad 8) has been the major and important causative agent of epidemic keratoconjunctivitis (EKC). By enzymatic cleavage analysis with five endonucleases, PstI, HindIII, BamHI, SalI and SstI, 27 out of 149 Ad 8 isolates recovered from patients with EKC during the period from July, 1980 to July, 1981 in Kaohsiung, Taiwan, were studied. By cleavage patterns, 27 Ad 8 isolates in Kaohsiung were classified into four subtypes which were found to be different from the subtypes (Ad 8A, Ad 8B) prevalent in Sapporo (1).

japanese journal of medical science and biology/japanese journal of medical science and biology

MOLECULAR EPIDEMIOLOGY OF ADENOVIRUS TYPE 8 (Ad 8) IN TAIWAN: FOUR SUBTYPES RECOVERED DURING THE PERIOD OF 1980-1981 FROM PATIENTS WITH EPIDEMIC KERATOCONJUNCTIVITIS