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Active reduced dose tetanus-diphtheria-acellular pertussis (Tdap) vaccination for adolescents and adults is necessary because waning immunity after primary diphtheria-tetanus-pertussis vaccination is related to the recent emergence of pertussis. This study was conducted to compare the immunogenicity and protection efficacy against Bordetella pertussis between a new GCC Tdap vaccine and a commercially available Tdap vaccine in a murine model.

clinical and experimental vaccine research

Preliminary study on the immunogenicity of a newly developed GCC Tdap vaccine and its protection efficacy against<i>Bordetella pertussis</i>in a murine intranasal challenge model

Preliminary study on the immunogenicity of a newly developed GCC Tdap vaccine and its protection efficacy againstBordetella pertussisin a murine intranasal challenge model