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T cell-mediated immune responses, and particularly activation of polyfunctional T cells that simultaneously produce multiple cytokines, are necessary for the control of Mycobacterium tuberculosis. In the present study, we examined if DNA immunization of Mycobacterium tuberculosis resuscitation-promoting factor B (RpfB) elicits polyfunctional T cell responses in mice.

DNA immunization ofMycobacterium tuberculosisresuscitation-promoting factor B elicits polyfunctional CD8+T cell responses

DNA immunization ofMycobacterium tuberculosisresuscitation-promoting factor B elicits polyfunctional CD8⁺T cell responses