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Retroperitoneal pseudocyst (RPC) is an uncommon surgical entity. The pseudocyst is characterized by the absence of epithelial lining in the cyst wall. Mostly, it occurs as a sequela of pancreatitis. Pseudocyst due to a non-pancreatic cause, however, is very rare.  We report a 49-year-old male, who presented to the emergency department with moderate intensity lower abdominal pain. Computed tomography scans revealed a huge retroperitoneal cyst which was overlying the right ureter and right iliac vessels. The patient underwent laparoscopic excision of the cyst and recovered without any complications. Histopathological examination showed a non-pancreatic RPC.  In conclusion, non-pancreatic RPC is a rare surgical disease which can result in pressure symptoms depending on its location and size. In our patient, it was treated by laparoscopic excision despite its proximity to iliac vessels and ureter.  A laparoscopic approach using safe surgical principles is a viable option for non-pancreatic RPC. The proximity of the lesion to the iliac vessels and the ureter can be carefully navigated safely by laparoscopy. The ureter can be confirmed by stimulating peristalsis of the duct when in doubt.

Idiopathic Retroperitoneal Non-pancreatic Pseudocyst in an Adult Male: Radiological Images and Surgical Video of Laparoscopic Excision