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Metastatic basal cell carcinoma (BCC) cases are rare and clinically challenging. We are reporting two such cases, which were seen at a short interval from one another, in order to outline and compare case features indicative of an aggressive BCC. Furthermore, we wish to discuss the role and delivery of radiation therapy in the treatment of this disease in the metastatic setting, including the use of stereotactic ablative radiotherapy. Finally, we address the use of vismodegib as it was made in these cases.

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Two Cases of Oligometastatic Basal Cell Carcinoma: A Comparison of Pathology Characteristics and Discussion of Systemic and Radiotherapeutic Management Strategies