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Aim: This work, based on the Spanish longitudinal growth and development series done at the Andrea Prader Center, Zaragoza, Spain, studied children up to the age of twenty years. It aims to contribute to a practical and accurate numerical method to calculate the bone age of the studied children, from birth to two and four years. Methods: The total sample of the study was 160 healthy children (73 males and 87 females). Every child underwent annual radiography on his/her left hand at the Miguel Servet Hospital in Zaragoza, Spain. Using measurements of the Tanner II-Rus method, the maximum epiphyseal distances of the subjects were studied. Results: As a result, we have developed an index called the Metacarpal-Phalanx Index, closely correlated with the chronological age of the child, which creates bone age prediction equations. Another index called "Index Valuation Ossification of the Metacarpal-Phalangeal", obtained through the above, allowed us to compare the results to Gaussian shape equivalences, thus revealing the ossifying status of the child, and whether it is late, early or insignificant.

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Biometric Method for the Ossification Evaluation of Children from Birth Up to the Ages of Two and Four – Applied to the Metacarpal and Phalanxes in Spanish Longitudinal Series