English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Fracture healing is the most common regeneration form in clinical practice. Bone as a tissue has the unique ability to heal itself without forming a scar. After the fracture, a chain of healing reactions is activated, both at the cellular and tissue level, that lead to full bridging of the gap between the two bony ends of the fracture. There are many immune cells that take part in this healing process and they play a significant role. There are three sequential phases to the process of fracture healing that remain independent. It has been revealed that the immune cells take part not only in the inflammation phase but also in the repair phase, where some of these cells act as intermediates to the transformation of soft callus to hard callus. In conclusion, immune cells serve as initial responders at the site of injury, restore vasculature, and initiate cascades of signals to recruit cells to carry out the repair processes. Thus the immune system can be considered a promising therapeutic target for bone fracture healing. Categories: Allergy/Immunology, Orthopedics

The Role of Immune System Cells in Fracture Healing: Review of the Literature and Current Concepts