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Trigeminal neuralgia (TN) is a nerve disorder of the face associated with excruciating pain that occurs in paroxysms and can be initiated by even mild cutaneous stimuli. Diagnosis of TN is based on the patient’s history and the diagnosis of exclusion. The first-line treatment usually comprises carbamazepine or oxcarbazepine. Herein we present a case of a 47-year-old female, diagnosed with idiopathic TN. Initially, she was commenced on carbamazepine, and later, she was switched to sodium valproate without any noticeable relief. However, she responded to treatment with combination therapy comprising antihistamine, montelukast, and corticosteroid nasal spray. To the best of our knowledge, no such case has been reported previously.

A Case of Trigeminal Neuralgia Treated With Combination of Antihistamine, Montelukast, and Corticosteroid Nasal Spray