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A Case of Soyangin Double Primary Cancer Patient with Adverse Reactions induced by Contrast Media So-Ra Park, Soo-Min Lee, Seong-Heon Choi, Jee-Young Lee, Sung-Un Lee, Yee-Hong Jung, Soo-Kyung Lee Cancer Center of Traditional Korean Medicine, Kyung-Hee University hospital at Gangdong, College of Korean medicine, Kyung Hee University Graduate school of Clinical Korean Medicine, Kyung Hee University Objectives Adverse reactions can becaused by contrast media used in computed tomography. The aim of this study was to report the improvement of allergic response caused by contrast media after treatment with Modified Hyeongbangpaedok-san, histamine antagonists and steroids. Methods We retrospectively reviewed the medical records. The patient’s subjective symptoms such as rash and pruritus were evaluated by the range of rash and numeric rating scale(NPS). Results All symptoms showed nearly complete remission with continued Korean traditional medical treatment. Conclusions A female patient had been injected with contrast media for Computed tomography(CT) evaluation of lung cancer. Rash and pruritus appeared 1 day after injection. We prescribed Modified Hyeongbangpaedok-san. Patients were treated with both Korean medicine and Western medicine. Consequently, the symtoms were improved significantly after combination treatment of Korean medicine and Western medicine.