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Objective: To explore gender differences in the clinical manifestations of patients hospitalized with\udacute exacerbations of chronic obstructive pulmonary disease (AECOPD), and to find independent risk\udfactors for their prognosis.\udMethods: Data from a retrospective study were analysed. Patients diagnosed with AECOPD were\udconsecutively enrolled from a respiratory ward from October 2010 to March 2012. The following\udclinical data were evaluated: body mass index (BMI), arterial blood gas analysis, pulmonary function\udtest during hospitalization or last pulmonary function test result before admission and exercise capacity.\udAll data were analysed using SPSS 13.0 statistical software. P-values of < 0.05 were considered\udstatistically significant.\udResults: One hundred and fifty-one patients hospitalized with AECOPD were enrolled. There were no\udsignificant gender differences in age, BMI, length of hospitalization, family history, exercise capacity,\udrespiratory failure, factors causing AECOPD, the number of antibiotics used during hospitalization or\udCOPD severity grade. Statistically significant differences were observed for cigarette smoking history,\udthe first clinical manifestations of the disease and chronic co-morbidities by gender. Gender was not an\udindependent risk factor for short- or long-term prognosis.\udConclusions: In patients hospitalized with AECOPD, there was statistical significance by gender for\udthe first symptom of the disease. Significantly more males were cigarette smokers than females.\udRegarding co-morbidities, the frequency of hypertension, diabetes mellitus and ischaemic heart disease\udwere significantly greater in females. For patients hospitalized with AECOPD, gender was not an\udindependent risk factor for short- or long-term prognosis

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Gender Differences in the Clinical Manifestations and Prognosis of Patients Hospitalized with Acute Exacerbations of Chronic Obstructive Pulmonary Disease