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A new approach to eradicating malaria is urgently required. Emphasizing vector eradication via larval control, we tried to find a safe concentration of copper, which can be utilized to reduce larval survival. It has been observed that mosquito larvae died when exposed to solid copper in water. We confirmed this phenomenon in our own experiments. We next studied the minimum copper concentration for effectively killing or disturbing Anopheles stephensi larvae. A concentration of 0.6 ppm had a significant impact on larval movement, making them vulnerable to predatory fish. Feeding time tests showed that guppies (Poecilia reticulata) ate the weakened larvae significantly faster than control larvae. Utilizing low concentrations of copper together with predatory fish in the field may shed new light on malaria eradication via vector control.

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Low-concentration copper solution jeopardizes larval movement and ability to survive predation: New insight into malaria eradication via vector control