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Background:    Campylobacter  infections may lead to serious conditions, including septicemia or other invasive forms of the disease, which require rapid and accurate laboratory diagnosis and subsequently appropriate antimicrobial therapy. The aim of this study was to compare the species distribution and antimicrobial susceptibility pattern of  Campylobacter  spp. strains isolated from patients and food samples.Methods:  Biochemical identification was performed on 15 clinical and 30 food isolates of  Campylobacter  recovered onto Brucella agar containing 5% sheep blood. PCR was carried out to confirm the identity of  Campylobacter  spp. using primers for  cadF ,  hipO , and  asp  genes of  Campylobacter . To determine antibiotic sensitivity of isolates, Kirby-Bauer assay was carried out using 16 different antibiotic discs.Results:  PCR assay and biochemical tests confirmed all 45 isolates as  Campylobacter : 20 (44.44%) as  C. jujeni , 10 (22.22%) as  C. coli , and 15 (33.34%) as other  Campylobacter  strains. The maximum resistance was observed to cefotaxime and imipenem (each 86.49%) and the maximum sensitivity to erythromycin (48.65%).Conclusion:    C. jujeni  is dominant among isolates from clinical and food samples. In addition, tetracycline remains the first-line therapeutic agent against  Campylobacter  infections in Iran.

Comparison of Antimicrobial Susceptibility of Campylobacter Strains Isolated from Food Samples and Patients with Diarrhea