Open AccessIgTools: a toolkit for construction of antibody repertoire using immunosequencing data
Author(s) -
Yana Safonova,
Ekaterina V. Starostina,
Alexander Shlemov
Publication year - 2015
Publication title -
faculty of 1000 research ltd
Language(s) - English
DOI - 10.7490/f1000research.1110260.1
Subject(s) - open peer review , plant biology , repertoire , computational biology , neuroscience , physiology , open data , antibody , biology , medicine , immunology , computer science , world wide web , botany , physics , acoustics
The analysis of concentrations of circulating antibodies in serum (antibody repertoire) is a fundamental, yet poorly studied, problem in immunoinformatics. Here we present IgTools, a collection of tools for construction and analysis of antibody repertoire using immunosequencing data. IgTools includes IgRepertoireConstructor, IgSimulator, IgQUAST, and Ig reperoire evolution analyzer. IgRepertoireConstructor and IgSimulator are freely available at Github. IgQUAST and Ig reperoire evolution analyzer will be released in fall 2015.
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