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. We conducted an in vivo experiment to study the effect of water-based infusion of Berberis lyceum and Silybum marianum on production performance and immune level of broiler chicks. A total of 120 day old broiler chicks was obtained from the same parent flock, and divided into four experimental groups i.e., WBI-0 (control), WBI-5 (5 ml/l), WBI-10 (10 ml/l) and WBI-20 (20 ml/l). Each group was further divided into three replicates with 10 chicks per replicate in a completely randomized design. The birds were reared in separate pens for 35 days in an open sided house. Low feed intake (P > 0.05) but higher weight gain (P   0.05) and feed conversion ratio (P > 0.05) were observed in group WBI-20. High level of antibody titre was also observed in group WBI-20 against the Newcastle and infectious bronchitis antigen, while significantly high (P

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&amp;lt;i&amp;gt;In vivo effect&amp;lt;/i&amp;gt; of &amp;lt;i&amp;gt;Berberis lyceum&amp;lt;/i&amp;gt; and &amp;lt;i&amp;gt;Silybum marianum&amp;lt;/i&amp;gt; on production performance and immune status of broiler chickens