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Mastitis is the most frequent and important disease in the dairy industry worldwide, which leads to great economic losses in the dairy industry (Nash et al. 2003). Direct selection for resistance to clinical mastitis may be very difficult and indirect selection has been practiced widely. The recommended measure is to record herd milk somatic cell scores (SCS) based on the positive correlation between clinical mastitis and milk SCS (Rupp et al. 1999)

A novel SNP of Lysozyme Gene and Its Association with Mastitis Trait in Chinese Holstein