Open AccessCurcumin Induces Caspase Mediated Apoptosis in JURKAT Cells by Disrupting the Redox Balance
Author(s) -
Priya Kalyan Gopal,
Mausumi Paul,
Santanu Paul
Publication year - 2014
Publication title -
asian pacific journal of cancer prevention
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 75
eISSN - 2476-762X
pISSN - 1513-7368
DOI - 10.7314/apjcp.2014.15.1.93
Subject(s) - curcumin , apoptosis , jurkat cells , dapi , intracellular , annexin , chemistry , microbiology and biotechnology , programmed cell death , cancer research , biochemistry , biology , immunology , t cell , immune system
Curcumin has has been reported to exert anti-inflammatory, anti-oxidation and anti-angiogenic activity in various types of cancer. It has also been shown to induce apoptosis in leukemia cells. We aimed to unravel the role of the redox pathway in Curcumin mediated apoptosis with a panel of human leukemic cells.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom