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Oral anticoagulant drugs (OALs) are eff ective agents in the prevention and treatment of thromboembolic complications. However, despite standardization and application progression, OALs represent a signifi cant clinical problem because they are small-therapeutic medicines that easily interact with food and medicine, which can substantially aff ect the increased or weakened therapeutic eff ect. Oral anticoagulants are 4-hydroxycoumarin derivatives and vitamin K antagonists, and their pharmacological activity is based on inhibition of the synthesis of coagulation factors in the liver. These drugs are eff ective in the prevention of venous thromboembolism, acute myocardial infarction (AIM), heart rhythm disorders by type of atrial fi brillation, stroke prevention, and the like. The most important and clinically commonly undesirable eff ect of OAL is bleeding. The risk of bleeding is greatest during the introduction of the drug in therapy and for the fi rst few months of the onset of therapy. HASBLED scor is a skoring system developed to estimate the 1-year risk of major bleeding in patients with atrial fi brillation and is also used for other indications.

sestrinski žurnal

HAS-BLED scor system for the assessment of risk of breathing of patients on oral anticoagulant therapy // HAS-BLED skor sistem bodovanja za procjenu rizika od krvarenja pacijenata na oralnoj antikoagulantnoj terapiji