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Periodic fluctuations in the size of the normal nasal mucosa were evaluated and analyzed by acoustic rhinometry. Seven healthy volunteers (males 4, females 3, average age 29 years, range 24 to 35 years) without any nasal lesions served as the subjects of this study. An acoustic rhinometry (GM Co.) was used, and each subject remained quiet in a sitting position for 5 hours. Nasal cross-sectional area was evaluated every 15 minites in a quiet, air-conditioned room. Periodic fluctuations in cross-sectional area were observed in 6 of the subjects, and the average cycle was 2.2 hrs.. No significant difference was seen between the genders. The anterior and posterior area of the nasal cavity were highly correlated (r: 0.94), demonstrating simultaneous swelling and shrinkage of the nasal mucosa. The minimal cross-sectional area was set equal to 100% as a baseline,and fluctuation on one side of the nose was 66-139%, and fluctuaion on both sides was 80-121%. Fluctuation in volume from the nasal entrance to a depth of 7cm was 69-143% on one side and 82117% on both sides. Fluctuation tended to be less on both sides, but the sum of values on one side did not show any constant areas, as suggested by rhinomanometry. This normal fluctuation of 70-140% in cross-sectional area and volume must be taken into consideration when applying acoustic rhinometry in clinical settings. All evaluations should be repeated at different times.

PERIODIC FLUCTUATIONS IN NASAL CROSS SECTIONAL AREAS AND NASAL VOLUMES ANALYSIS BY ACOUSTIC RHINOMETRY