English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

Until now, an in vitro measurement of serum specific antibody is widely used for the diagnosis of symptomatic antigen of nasal allergy. When the serum contained more than 1 or 2 of score for a specific antigen, in whichever method used, it could be diagnosed positive. However, we experienced that some patients had no symptom or no nasal antigen provocative reaction especialy when they were sensitized with other antigen (s). We studied relationships between perennial, seasonal, and both symptoms, using the serum IgE measurement by CAP-RAST in 471 patients sensitized by HD/mite, Japanese ceder pollen (JCP), or both. The appearance rate for seasonal symptoms was dependent on the serum concentration of the JCP IgE. However, the rate of seasonal symptoms was reduced dependenting on the serum concentration of HD/mite IgE. The reverse was true between the perennial symptom rate in patients with serum HD/mite IgE and the serum JCP IgE. It was possible that the antigen induced histamine release from nasal mast cells of patients sensitied by only one antigen was different from patients sensitized by a second or other antigens. We studied the histamine releasability by using nasal scrapings from 10 patients. Mite-induced histamine releases from nasal scrapings of patients sensitized with HD/mite (score 2 and 3) and JCP (score 4) which were less than those of patients sensitized with only HD/mite (score 2 and 3). From these results, we concluded that we could not diagnose a symptomatic antigen from an in vitro measurement of an antigen IgE but rather form IgE levels of at least several antigens, and using patients with detailed histories.

Can symptomatic antigen of nasal allergy be diagnosed from the level of the serum IgE antibobody?