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Epidermal inclusion cysts are the most common keratin containing cyst found in the skin leading sebaceous cysts and dermoid cysts. They are often referred to as implantion cysts since their major histiogenesis depends on the implantation of epidermis into the dermis following trauma. Carcinoma is ubiquitous, but rarely seen developing from the epithelium of epidermal inclusion cysts. Herein we report a case of a squamous cell carcinoma developing from an abdominal wall epidermal inclusion cyst.

Squamous cell carcinoma developing in an epidermal inclusion cyst